home

= __ Paget's Disease of the Bone __ = =NAMES:= ====Paget's Disease of the Bone is also known as Osteitis Deformans. Paget's disease can develop in any bone in a person's body bust most people have it in their spine, pelvis, skull, thigh (femur), collar bone (clavicle), or upper arm (humerus).====



The disease can affect one to several bones at once but it does not affect the entire skeleton. Paget's disease is named after an English surgeon and a pathologist named Sir James Paget. About one million people in the United States have Paget's disease.

**CAUSES:** ====Does not really have a known cause to it, but recently researchers believe it has been caused by a virus infection inside the bone. Also doctors believe that Paget's disease tends to be hereditary. ====

=AGE RANGE IT AFFECTS:=

It is also common in people of Northern European descent and it is almost nonexistent among people of Asian and African descent.
= SYMPTOMS: = ==== Doctors say most people with the disease have no symptoms except pain wherever the disease is affecting the bone but usually if the disease affects the skull it can result in headache, blindness, and deafness. Also is the disease becomes very severe it can result in heart failure. ==== =DIAGNOSIS:=

To diagnose the disease doctors either get an X-ray, MRI scan, or CT scan or they do a blood test for any elevated level of an enzyme called alkaline phosphatase.
=FATALITIES:= ====The Paget's disease isn't fatal however it is a long lasting condition that occurs more in men. Doctors say the outlook of the disease is good especially if its diagnosed and treated before the major changes in the bone have occurred.==== =MEDICAL TREATMENTS:=

While in an early age this disease could be treated by exercise, maintaining normal body weight, surgery and medications that include bisphosphates, calcitonin, NSAIDS, and plicamycin.
=HOME REMEDIES:=
 * ====Prevent falls====
 * ====Eat well====
 * ====Exercise regularly====
 * ====Get a lot of Vitamin C and D====

=SYSTEMS & ORGANS THE DISEASE AFFECTS:=

The Paget's disease affects the skeletal system.
=﻿HOW DOES IT AFFECT THE SYSTEMS & ORGANS?:=

Paget's disease affects the bone by slowly progressing bone disorder which overtime the bone is rapidly being destroyed and replaced by an abnormal bone which is dense and fragile.
=﻿TWO FACTS ABOUT PAGET'S DISEASE:=

2) The disease does not spread to other bones.
=﻿TEST QUESTIONS:=

2) What is another name for Paget's disease of the bone?

 * = NORMAL X-RAY OF KNEE BONE: = || = PAGET'S DISEASE OF KNEE BONE: = ||
 * [[image:normal_x-ray.jpg width="370" height="495"]] || [[image:x-ray.jpg width="330" height="495"]] ||

= ﻿WORKS CITED = ==== ﻿ 1) NIH National Resource Center. "Fast Facts About Paget's Disease of Bone." //Arthritis, Musculoskeletal and Skin Diseases Home Page//. NIH National Resource Center. Web. 13 Dec. 2010. [].====

2) Ralston, S. "Pathogenesis of Paget's Disease of Bone." //Bone// 43.5 (2008): 819-25. Print. //3) "**Paget disease of bone**." __Encyclopædia Britannica__. 2010. Encyclopædia Britannica Online. 13 Dec. 2010 <[]>.//

//4) Shiel Jr., William C. "Paget's Disease of Bone."// Paget's Disease Symptoms, Diagnosis, Treatment, Causes and Prognosis on MedicineNet.com//. Web. 13 Dec. 2010. .